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periocin periodontal therapy for dogs and cats

Local Antibiotic Therapy for Periodontal Disease in Dogs & Cats

Periocin

Helping dogs and

cats live longer

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periodontitis tooth loss dogs and cats

Treat your pet's gum disease

Gum disease is the leading cause of tooth loss in adult dogs and cats

Bacteria from the mouth can enter the bloodstream and spread throughout your pet's body. In fact, recent studies link gum disease in dogs and cats to a shorter lifespan, as well as heart, lung, and kidney disease.

Periocin gum local therapy for dogs
Periodontal gum treatment for cats
periodontitis dogs and cats malnutrition

Have questions about gum disease? Chat with us!

Is your pet having trouble chewing their food?

Adult dogs and cats suffering from tooth loss due to severe gum disease are forced to change how they eat. Over time, this difficulty chewing can lead to malnutrition. When left untreated, gum disease isn't just painful for your pets - it can wreak havoc on their entire body.

periodontal disease most common disorder cats and dogs

Gum disease is the most common health issue affecting cats and dogs

If your pet happens to have periodontitis, it’s time to get busy! While there is no known cure for periodontal disease in dogs and cats, just like diabetes, it can be managed and controlled with the Periocine periodontal maintenance program.

Periodontitis treatment for cats
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Bleeding Gums

Did you know that over 80% of dogs develop gum disease by the age of three?

Most dogs and cats with periodontitis will show signs of redness, swelling, and bleeding along the gums at the base of the teeth. They may also be reluctant or unwilling to eat, drool, turn their heads to the side when chewing, and develop bad breath (halitosis).

How Our Targeted Gum Treatment Works (Watch the Video Below)

Periocin uses advanced nanoparticle technology to deliver targeted relief directly to your pet's gums. The medication is packed into tiny microcapsules containing the active ingredient, minocycline.

 

Once applied to the gum pocket, these capsules slowly dissolve, releasing a steady dose of medication for at least 14 days. The special polymer that holds the medicine serves three vital purposes: it controls the release of the drug, helps the treatment stick securely to the gums, and keeps the medication stable. Once finished, the capsule naturally and safely dissolves into the body.

minocycline microspheres sustained release

Formulated for deep tissue penetration

The medication absorbs deeply into the infected gum pockets. With a 37.5% improvement, our minocycline microspheres set a new industry-leading standard for formulation purity.

periodontal local therapy dogs and cats

Protecting the Tissue That Holds Teeth in Place

Periocin helps damaged gums heal and securely reattach to the tooth.

Periocin minocycline microspheres for pets
killing bacterial gum disease dogs and cats

Fights infection 24/7 for 14 straight days

Even the best veterinarian can only do so much. Minocycline Nanospheres are among the most effective agents against the bacteria associated with periodontitis.

 

The polymer shell begins to slowly dissolve, thereby releasing minocycline at a sustained rate for at least 14 days.

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topical antibiotic for dogs and cats gum disease

Targeted Therapy vs. Oral Antibiotics

Applying medicine directly to the gums is the most effective way to treat the infection. While traditional antibiotic pills have to travel through your pet's entire body, our targeted approach goes straight to the source.

 

Periocin delivers a powerful, concentrated dose right where it's needed, keeping your pet safer and reducing the risk of antibiotic resistance.

Dog Lover
periocin powder medicine for periodontitis dogs and cats

DESIGNED FOR YOUR PET'S COMFORT 

The applicator ensures the precise and painless delivery of the powder medication. Its smooth, blunt tip is designed to easily slide between the tooth and gums, gently opening the pocket to place the time-released medicine exactly where your pet needs it most.

Dog and his Vet
minocycline microspheres technology dogs and cats gingivitis

SUPPORTING YOUR VETERINARIAN'S EXPERT CARE

Periocin works a lot like the dissolvable stitches your vet uses. Our tiny microspheres safely and slowly break down in your pet's mouth, releasing a steady stream of medicine to fight off bacteria while the gums heal.

Pets live longer with healthty gums

HELP YOUR PET LIVE LONGER WITH HEALTHY GUMS

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Research shows a direct link between the number of teeth your pet keeps and their overall life expectancy. In fact, left untreated, severe periodontal disease can shave up to two years off a dog or cat's life.

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Here are three vital ways Periocin helps protect your pet's health and longevity:

  • Stops the Spread: By fighting infection at the source, Periocin prevents harmful oral bacteria from traveling to other vital organs.

  • Restores Comfort: Relieving mouth pain and discomfort instantly improves your pet's daily quality of life.

  • Protects Their Bite: Keeping teeth and gums healthy ensures your pet can comfortably eat and chew their favorite foods.

Ask Your Vet About Periocin

How PERIOCIN Targeted Gum Treatment Works

Benefits of Minocycline Microspheres Perioceutics

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Engineering Effective Periodontal Preservation

Owning a pet may reduce your brain age by up to 15 years

We don't have to tell you that your furry companion is good for your health, but it turns out science agrees!

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  • A Younger Mind: Studies show owning a pet can improve cognition and actually reduce your brain age by up to 15 years (especially for dog owners and those with multiple pets!).

  • A Stronger Heart: Whether you're a dog devotee or a feline fan, pets are great for your heart. Research shows that dog ownership significantly lowers the risk of recurrent heart issues, while a 20-year study found that cat owners have a vastly decreased risk of strokes and cardiovascular disease.​

 

So, give your pet an extra treat today—and thank them for helping you live a healthier, happier life. (The study link)

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THE PERIODONTAL APPLICATOR IS A STAND-ALONE, FDA-REGISTERED MEDICAL DEVICE MANUFACTURED IN AN FDA-REGISTERED FACILITY IN FULL COMPLIANCE WITH CURRENT GOOD MANUFACTURING PRACTICES (CGMP). HOWEVER, THE INVESTIGATIONAL DRUG PRODUCT PERIOCIN, AS A COMBINATION PRODUCT, HAS NOT YET BEEN APPROVED BY THE FDA AND IS NOT CURRENTLY AVAILABLE FOR SALE IN THE UNITED STATES.

© 2026 PharmaPhD II, LLC. This Site, PharmaPhD word mark, PharmaPhD logo, and the information contained and referenced therein are copyright protected. PharmaPhD is a registered trademark and any copy, reproduction, republication, upload, translation, retransmission, or other domestic use is strictly prohibited. 

IMPORTANT SAFETY INFORMATION

Do not give minocycline to your dog and cat if they are allergic to minocycline or tetracyclines. Ask your veterinarian for a list of these drugs if you are not sure. Tell your veterinarian right away if your pet has any signs of allergic reaction, such as skin reactions or trouble breathing.

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IMPORTANT LEGAL, REGULATORY, AND FINANCIAL DISCLOSURES
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Investigational Status & Regulatory Notice Periocin™ is an investigational drug-device combination product. It has not been cleared, approved, or granted marketing authorization by the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), or any other global regulatory authority. Caution: Limited by Federal (United States) law to investigational use. The safety and efficacy of Periocin™ have not been established. All statements herein regarding potential mechanisms of action, safety profiles, clinical efficacy, or therapeutic outcomes are provisional, exploratory in nature, and strictly contingent upon the successful completion of rigorous clinical trials and definitive regulatory review. Pursuant to the Federal Food, Drug, and Cosmetic Act (FD&C Act) and related global statutes, Periocin™ is restricted to investigational application and is expressly prohibited from commercial sale, distribution, promotion, or clinical use in any jurisdiction.

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Safe Harbor & Forward-Looking Statements Certain content provided herein constitutes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 (PSLRA) and applicable global securities laws. These statements encompass, but are not limited to, projections regarding regulatory classification and authorization pathways (including FDA Office of Combination Products (OCP) Request for Designation (RFD) submissions, Section 513(g) classification inquiries, and subsequent clearance or approval strategies), intellectual property prosecution, clinical development timelines, and commercial market potential. Such statements are identifiable by terminology including, but not limited to, “anticipates,” “believes,” “expects,” “intends,” “projects,” “forecasts,” “estimates,” or similar predictive expressions. These forward-looking statements are predicated on current management assumptions and are subject to severe biological, regulatory, clinical (including potential clinical holds), economic, and competitive risks that could cause actual outcomes to diverge materially from projected results. PharmaPhD II, LLC expressly disclaims any legal obligation or undertaking to update or revise any forward-looking statements to reflect subsequent events, new information, or changing circumstances, except as strictly required by law.

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No Offer of Securities, General Solicitation, or Reliance The information provided herein is published exclusively for corporate, scientific, and strategic evaluation purposes. It does not constitute, nor shall it be construed as, a prospectus, an offer to sell, or a solicitation of an offer to buy any securities, equity, debt, or assets of PharmaPhD II, LLC in any jurisdiction, nor does it constitute a "general solicitation" or "general advertising" under Regulation D of the Securities Act of 1933, as amended. No content herein shall form the basis of, or be relied upon in connection with, any contract or investment decision. Any future strategic transactions, capital raises, licensing agreements, joint ventures, or divestitures will be executed exclusively pursuant to definitive, legally binding documentation containing comprehensive risk disclosures, strictly in compliance with applicable corporate and securities regulations.

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Medical Disclaimer & Scientific Exchange The materials presented are intended solely for scientific discourse, institutional peer review, and strategic partner evaluation, constituting protected scientific exchange. They do not constitute, and must not be construed as, professional medical, dental, or clinical advice, diagnoses, or treatment protocols. Healthcare professionals and patients must not utilize or rely upon this information for medical decision-making or in lieu of established standards of care. No doctor-patient relationship is established by the dissemination or review of this content.

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Intellectual Property, Copyright & Trade Secrets Copyright © 2026 PharmaPhD II, LLC. All rights reserved. Periocin™, PerioER™, and their respective logos are trademarks of PharmaPhD II, LLC. All associated formulations, device architectures, delivery mechanisms, manufacturing processes, and proprietary clinical data are protected by issued patents, pending patent applications, trade secrets, and other exclusive intellectual property rights owned by PharmaPhD II, LLC. Unauthorized reproduction, dissemination, public display, reverse engineering, or commercial exploitation of any information or concept contained herein is strictly prohibited and will be prosecuted to the fullest extent of the law.

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Limitation of Liability By accessing this information, the recipient acknowledges and agrees that PharmaPhD II, LLC, its officers, directors, employees, and affiliates shall bear no liability for any direct, indirect, incidental, special, or consequential damages arising from the reliance on, use of, or inability to use the information provided herein.

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